Contact Us
Whether you’re reaching out with a general question or need directions to our office, we’re here to help. At Piedmont Arthritis Clinic, we want every patient-and every referring provider-to feel supported, informed, and at ease.
A Quick Note
Current patients: For medical questions, appointment requests, or prescription refills, please use our Patient Portal. It is a much quicker and convenient way to communicate with us.
Referring providers: Please visit our Referrals Page to send patient information securely.
Send Us a Message
Have a non-urgent question for our front desk team? Use the form below to get in touch. We’ll get back to you as soon as we can during business hours.
Our Office
We’ve Moved! Starting on July 20th, 2026, we see all of our patients at our new location. For the address and driving directions, see below.
Piedmont Arthritis Clinic
50 International Drive, Building 3, Suite 325
Greenville, SC 29615
Phone: 864.235.8396
Fax: 864.271.4092
Office Hours
Monday – Friday: 7:30 AM – 5:00 PM
Saturday & Sunday: Closed
Saturday & Sunday: Closed
Our New Office Location:
50 International Drive | Building 3, Suite 325 | Greenville, SC 29615
Driving Directions to Our New Office:
Turn left onto St Francis Dr.
Turn right onto Easley Bridge Rd (US-123).
Turn left onto E North St (I-385-SPUR) toward Columbia/I-385-TRUCK/Spartanburg
Keep left onto I-385 S toward I-385/Spartanburg/Columbia.
Take exit 39 toward Haywood Rd.
Turn left onto Haywood Rd.
Turn right onto Pelham Rd.
Turn right onto Roper Mountain Rd Ext.
Turn right onto Commonwealth Dr.
Turn left onto International Drive.
Turn right into parking lot. The NEW office is in front of you, Building 3, Suite 325!
Take I-85 S.
Take exit 54 toward Pelham Rd onto Pelham Rd.
Turn left onto Roper Mountain Rd Ext.
Turn right onto Commonwealth Dr.
Turn left onto International Drive.
Turn right into parking lot. The NEW office is in front of you, Building 3, Suite 325!
Start on US-123 N.
Turn left onto E North St (I-385-SPUR) toward Columbia/I-385-TRUCK/Spartanburg.
Keep left onto I-385 S toward I-385/Spartanburg/Columbia.
Take exit 39 toward Haywood Rd.
Turn left onto Haywood Rd.
Turn right onto Pelham Rd.
Turn right onto Roper Mountain Rd Ext
Turn right onto Commonwealth Dr.
Turn left onto International Drive.
Turn right into parking lot. The NEW office is in front of you, Building 3, Suite 325!
Take I-26 W toward Spartanburg.
Take left exit 51 toward I-385/Laurens/Greenville onto I-385 N
Take exit 37 toward Roper Mtn Road/Hospital.
Turn right onto Roper Mountain Rd toward Hospital.
Turn left onto Roper Mountain Rd Ext.
Turn left onto Commonwealth Dr.
Turn left onto International Drive.
Turn right into parking lot. The NEW office is in front of you, Building 3, Suite 325!
Take I-26 E.
Take exit 54 toward Greenville/US-176/NC-225 onto US-25 S (US 25 Hwy).
Continue on US-25 S.
Keep left onto Poinsett Hwy (US-276 E) toward Greenville.
Turn left onto State Park Rd (SC-253).
Continue on N Pleasantburg Dr (SC-291).
Turn right onto N Pleasantburg Dr (SC-291).
Turn left onto E North St.
Turn slightly right onto Pelham Rd.
Turn right onto Roper Mountain Rd Ext.
Turn right onto Commonwealth Dr.
Turn left onto International Drive.
Turn right into parking lot. The NEW office is in front of you, Building 3, Suite 325!
Accessibility Information
We want your visit to be as comfortable and accessible as possible.
Our office is:
Located on the 3rd floor with elevator access
Wheelchair accessible, including building entry and restrooms
Equipped with ample
parking, including designated accessible spaces near the entrance
If you have specific accessibility needs or questions before your visit, feel free to call us at 864.235.8396. We’re happy to help.
Frequently Asked
Questions
Yes! We welcome new patients with a referral from your physician. Visit our Referrals Page to get started.
We’re in-network with many major providers, including:
- Medicare
- Blue Cross Blue Shield
- Cigna
- Aetna
- Humana
We also accept many Medicare Advantage plans. To be sure we’re in-network with yours, contact your plan administrator before your appointment.
